IUPUI is Indiana's premier urban research university. The campus enrolls more than 30,000 students in 21 schools and academic units.
Jake Chen
Assistant Professor of Informatics & Computer Sci.
School of Informatics
jakechen@iupui.edu
Translational Systems Biology Research
We develop computer software tools to model molecular interaction networks of complex human genetic disorders such as Alzheimer's Disease and cancer. This research allows the development of drug targets that can serve as panel of molecular biomarkers that can predict the early onset of these complex human diseases and monitor their progression. The research, "Systems and Network Biology", is based on collecting experimental data publicly available for tens of thousands of molecular entities such as genes and proteins. It's highly interdisciplinary, requiring skill sets from molecular biology, human genetics, applied statistics, machine learning, and high-performance software engineering. When successful, it enables future medical professionals to develop better drug compounds focusing on likely targets and biomarker molecules for better diagnostic applications.
