Bantz-Petronio Translating Research into Practice Awards

2023 Bantz-Petronio Translating Research into Practice Award

The 2023 Bantz-Petronio Translating Research into Practice Faculty Award recipient is Holly Cusack-McVeigh, Ph.D. Dr. Cusack-McVeigh is an associate professor of Anthropology and Museum Studies and Public Scholar of Collections and Community Curation in the IU School of Liberal Arts with an appointment in the Native American & Indigenous Studies Program. Her scholarly research is deeply grounded in social justice and centered in an interdisciplinary, community-based collaborative approach to address real-world issues. The goal of her translational research is to forge connections and foster lasting community partnerships that bring about greater cultural understanding and social change in local, national, and international communities. Dr. Cusack-McVeigh and her research team work on toxic museum collections and the repatriation of Indigenous cultural heritage artifacts. 

Many museum collections contain artifacts that are potentially hazardous to the health and safety of employees, volunteers, visitors and community members due to prior toxic chemical treatments. However, many museum professionals are not trained to properly care for such items. Through Dr. Cusack-McVeigh's transdisciplinary research, she collaborates with scholars and practitioners across institutional boundaries to advance the understanding of these risks, and to identify methods of assessment, and mitigation of these different toxic collections. 

Dr. Cusack-McVeigh’s work on national and international repatriation is groundbreaking. In 2014, Dr. Cusack-McVeigh worked with the FBI Art Crime team to seize 7,000+ artifacts from the Don Miller collection in Waldron, Indiana. The illegally looted cultural objects represented the largest case to date for the FBI Art Crime team. For almost a decade, Dr. Cusack-McVeigh and her IUPUI students have worked to identify the cultural origin of items, coordinating returns to descendant communities and caring for the collections in a temporary, undisclosed location. This work is extraordinary in many ways, not the least of which was the complications of working across international boundaries, a myriad of foreign laws, diplomatic relations, and cultural protocols and all within the constraints of FBI law enforcement practices. Not only have thousands of objects and human ancestral remains been repatriated around the world, but relationships have been repaired. Her work on multiple FBI cases has truly influenced US policy and practice relating to the respectful treatment and repatriation of cultural property and ancestral remains. 

As an educator, Dr. Cusack-McVeigh's translational research strongly influences the way in which she teaches her students to be civically engaged through applied learning. She creates immersive, hands-on learning experiences. She offers her students unparalleled opportunities to become self-reflective and engaged leaders through experiences both in and out of the classroom. Her students receive real-world experience and learn the importance of strong leadership that integrates a collaborative and inclusive approach to cultural heritage. Embedding real-world, team-based experiences throughout the semester, and not just as a field trip or summer internship, is innovative in that students are tasked with both learning and applying the course lessons every week not just as a one-time learning lab experience. 

Since joining the IUPUI faculty in 2012, Dr. Cusack-McVeigh's research has exemplified the principles and achieved the results of translational research. Her integrated research and teaching practice is interdisciplinary and oriented towards improving quality of life in communities and organizations in central Indiana and around the globe. Her work is engaging, innovative, and she is leading the cultural heritage field in transforming practices. 

Dr. Cusack-McVeigh stated, “It is such an honor to be recognized with this award and to follow in the footsteps of Chancellor Bantz and Professor Petronio, scholars who paved the way for those of us who center our research in an interdisciplinary, community-engaged approach to addressing problems that impact our local and global communities.” 

Congratulations Dr. Cusack-McVeigh!

2022 Bantz-Petronio Translating Research into Practice Award

The 2022 Bantz-Petronio Translating Research Into Practice Faculty Award recipient is Todd Skaar, PhD. Dr. Skaar, an internationally recognized leader in the field of pharmacogenomics, received this award in recognition of his groundbreaking research and his dedication to mentoring the next generation of translational scholars. Dr. Skaar is a professor of medicine in the IU School of Medicine and a co-leader at the Cancer Prevention and Control & Symptom Science Program of the Indiana University Melvin & Bren Simon Comprehensive Cancer Center. He also currently serves as the interim chief of the Division of Clinical Pharmacology, an internationally recognized division of expert investigators in drug therapies.

Dr. Skaar and his research team study ways to improve the success of cancer treatment drug therapies.  His work focuses on the impact of genomic variability in how these drugs interact with each other and in the body. Better understanding these drug interactions can improve outcomes and reduce hospitalizations. Dr. Skaar’s competitive translational research was awarded an NIH-funded Maximizing Investigators’ Research Award (MIRA).

Dr. Skaar serves as the leader of the Pharmacogenomics (PGx) Implementation Team working under the larger Precision Health Initiative (PHI) inaugural project awarded in 2016. PGx, which utilizes a patient’s genetics to guide selection and dosing of appropriate medications, has the potential to enhance medication efficacy and minimize toxicity. Dr. Skaar’s team has successfully implemented PGx testing in cardiology, oncology, psychiatry, neurology, and in various transplant disciplines.

In addition to a robust research portfolio, Dr. Skaar also has more than 150 indexed publications in PubMed and has authored numerous clinical practice guidelines as a member of the Clinical Pharmacogenetics Implementation Consortium, an expert organization whose mission is to provide evidence-based guidance on how to translate genetic results into actionable prescribing decisions.

Dr. Skaar is passionate about mentoring and encouraging young researchers. Trainees have emerged as leaders in translational medicine, as faculty at academic institutions, as scientists working in the pharmaceutical and biotechnology industries, and as regulators at the U.S. Food and Drug Administration and National Institutes of Health. Dr. Skaar exemplifies a translational scientist through his research, collaborations, mentorship of trainees, and through his positive impact on human health.

Congratulations Dr. Skaar!

2021 Bantz-Petronio Translating Research into Practice Award

The 2021 Bantz-Petronio Translating Research into Practice Faculty Award recipient is Dr. Gerardo Maupome, an IUPUI TRIP Scholar with extensive expertise in public health and community-based translational research. Dr. Maupome is the Associate Dean of Research in the Richard M. Fairbanks School of Public Health. Additionally, Dr. Maupome has conducted high impact interdisciplinary and cross-disciplinary research that has generated new knowledge and positively influenced the health of Indiana residents and beyond.

Dr. Maupome’s research has been conducted with strong and longstanding community partnerships that he has worked hard to establish and maintain. Building on his clinical background, Dr. Maupome has demonstrated a commitment to exploring and modifying the social and behavioral aspects of health and disease. He has conducted clinical trials to test the tooth decay-protective effect of antiseptic varnishes painted on teeth of American Indian adults as well as comparative evaluations of the longevity of dental fillings in young American children. He has compared treatment preferences for dentures among Swedish and Canadian elders and examined the role of social support and social networks. He has partnered with American Indian tribes in the Pacific Northwest to reduce the consumption of sugared beverages demonstrating their effects on tooth decay among toddlers and tweens. He has designed a culturally-targeted intervention to help Central American nationals navigate the health care system in Indiana.

Collectively, Dr. Maupome has received or collaborated in research supported by over $14 million dollars in external funding from sources such as the National Institutes of Health, the Indiana Clinical and Translational Sciences Institute (CTSI), the Centers for Disease Control and the American Dental Association Foundation.

Dr. Maupome has published over 230 peer-reviewed, data-based publications. And, he has led or co-authored 268 presentations at local, regional, national and international conferences. Additionally, he strongly believes in supporting the next generation of translational researchers by mentoring students, junior faculty, and community members.

Dr. Maupome is committed to understanding health disparities through examining social networks and living conditions and enhancing the quality of life for all human beings, especially those with limited resources and opportunities.

Congratulations Dr. Maupome!

2020 Bantz-Petronio Translating Research into Practice Award

Peter Schubert, PhD, was awarded the 2020 Bantz-Petronio Translating Research Into Practice Award for translating his research into practical solutions for affordable and reliable energy from renewable sources. The university created the spin-up company Green Fortress Engineering (GFE) to commercialize his intellectual property on waste-to-energy, hydrogen storage, and in-space resource utilization. The biomass gasifier he invented has been funded by the USDA, the Department of Energy, and the Army, and has earned five US patents. Using locally-available low-cost materials such as crop waste, food waste, and utility trimmings, his technology can produce electricity, heat, biochar, and hydrogen gas. The gasifier is called the Stalk Stoker, and is suitable for farms, factories, and facilities which have free or nuisance materials available. 

The bio-hydrogen can be stored in a novel solid-state storage media for which Schubert holds four US patents. The research has been funded by the DOE and the National Science Foundation. GFE has received further development funds from private industry, subcontracting the research components to IUPUI while developing commercial applications for fuel cell vehicles and long-duration aerial drones. This approach is eight times better than batteries, and could revolutionize how we generate, store, and transport energy.

Schubert’s most out-of-this-world technology is converting mineral resources from the moon and asteroids into solar power satellites.  When placed in a geosynchronous orbit they can beam power to cities on earth around the clock. With abundant clean and inexhaustible power to urban centers, paired with local waste-to-energy in rural and remote locales, his translational research is a very practical exemplar of how IUPUI's faculty members seek to make our communities better.

Dr. Schubert is Professor of Electrical and Computer Engineering in the Purdue School of Engineering and Technology and serves as Director of the Richard G. Lugar Center for Renewable Energy and CEO of Green Fortress Engineering, Inc.

Congratulations Dr. Schubert!

2019 Bantz-Petronio Translating Research into Practice Award

 

ray bradBrad Ray, Ph.D., was awarded the 2019 Bantz-Petronio Translating Research into Practice Award for his noteworthy research and work on the intersection of substance abuse and mental health in the population within the criminal justice system. This work has focused on interventions in behavioral health as well as health-related outcomes from opioid-related overdoses. Dr. Ray’s work revealed that social factors such as poverty contributed to the daily issues and challenges experienced by individuals, which in turn led to substance abuse.

Dr. Ray joined IUPUI in 2012 as an assistant professor in the Paul H. O’Neill School of Public and Environmental Affairs. Subsequently promoted to associate professor with tenure, he became Director of the Center for Health and Justice Research (CHJR) within the Indiana University Public Policy Institute (PPI) in 2016.

Dr. Ray has been an active community-engaged scholar and has authored many blog posts and over 40 published articles. His translational research includes a collaboration with Mental Health Courts to develop rehabilitation-based approaches to better help individuals in the criminal justice system. Dr. Ray also completed a 10-year study on opioid-related overdoses, which was the first spatial study of overdoses. In order to translate this research into practice for Indiana, he developed many relationships and community partnerships including with the Indianapolis Metropolitan Police Department (IMPD) in the Southwest District. One result was dubbed “The Heroin Roundtable,” a group that has promoted several programs to improve the recognition of overdose signs through training of personnel. 

Dr. Ray partnered with the community to gain a better understanding of fatal and nonfatal opioid overdoses, vital records data, correlations between opioid use and criminal behavior, and trends in use. His partnership with the Indiana State Department of Health, the Centers for Disease Control and Prevention, the Marion County Coroner’s Office, and Indiana lawmakers resulted in the passage of Indiana Senate Enrolled Act 139. This act requires the coroner’s office to test for opioid overdoses in suspicious deaths. Data from this registry will help the state better understand and treat opioid use and its related challenges.

We thank Dr. Ray for all his contributions to make our communities safer and healthier. 

Congratulations Professor Ray!

2018 Bantz-Petronio Translating Research into Practice Award

Sunil Badve, MBBS, MD (Path), FRCPath (Engl), was awarded the 2018 Bantz-Petronio Translating Research into Practice Award in recognition of his exemplary translational research in the area of breast cancer.

Dr. Badve's translational research efforts on efficient treatment of breast cancer have a two-pronged approach; developing novel targeted therapies on the one hand and identifying ineffective therapies on the other. His team is studying the individual biological components that culminate in cancer. Gaining a better understanding of these molecular mechanisms will enable identification of key "nodes" in cellular pathways, which can then be targeted by biological agents leading to better diagnosis and effective treatment of breast cancer.

Dr. Badve demonstrated that the FoxA1 protein plays a critical role in determining responses to anti-hormonal therapy IU patent, being licensed. His group has developed a gene signature useful for predicting brain metastasis (IU patent pending) and is currently, with (IU and non-IU) collaborators, trying to dissect the pathways associated with brain metastasis with the hope of preventing and treating this disease. He is also collaborating with IU and Purdue researchers to develop novel methods of detecting and treating breast cancer.

His practical application of research into information that can be used by local clinicians in treating breast cancer is a unique and important contribution to our understanding of cancer and successful treatment approaches.


Congratulations, Professor Badve!

2017 Bantz-Petronio Translating Research into Practice Award

Mark R. Kelley, PhD, was awarded the 2017 Bantz-Petronio Translating Research into Practice Award in recognition of his exemplary translational research in the area of cancer.

Since joining the Department of Pediatrics at the IU School of Medicine in 1993, Dr, Kelley’s work has focused on translational research in DNA damage and repair, specifically, to determine how those activities can be exploited therapeutically to treat cancers and protect normal cells from DNA damage.

He has focused specifically on the enzyme called APE1 as a therapeutic target in cancers and other diseases. Dr. Kelley discovered and has been developing a specific inhibitor of APE1 which he is now translating to clinical trials. This work has also led to the creation of a biotechnology company called Apexian Pharmaceuticals, of which Dr. Kelley is the Chief Scientific Founder and Officer.

The first drug developed has recently been approved by the FDA for Phase 1 clinical trials in cancer patients scheduled to begin in 2017. The drug has potential uses in a number of cancers including ovarian, colon, bladder, pancreatic, leukemia, and other adult and pediatric cancers.

He is also exploring the use of the target APE1 and the drug to prevent a major side-effect of cancer treatments called chemotherapy-induced peripheral neuropathy (CIPN).

Dr. Kelley is committed to fast-tracking collaboration and translational research efforts in order to find more effective cancer treatments. He also mentors and encourages students, post-doctorates, fellows and junior faculty in translating their research into practice to expand the number of discoveries that help solve problems and make life better.

Congratulations, Professor Kelley!

2016 Bantz-Petronio Translating Research into Practice Award

Patricia Scott, PhD, was awarded the 2016 Bantz-Petronio Translating Research into Practice Award based on her outstanding translational research.

Roles are sets of activities performed in a routine way, for example, work, friendship, volunteerism, hobbyist, or maintaining a home. The roles we participate in structure our lives, and govern the way we see ourselves and others see us. As life moves forward we develop habits and routines that enable us to meet the expectations of these various roles. Roles are the ‘how’ of social participation. Human beings we are social in nature, and make choices based on our interests and values. Through this social interaction we identify ourselves through roles such as "I am a student at IUPUI" or "this is my sister Joanne" and "David is an engineer who works with my brother-in-law."

As an occupational therapist, Dr. Scott treated people with problems stemming, in part, from lack of participation in valued roles. Many of these people have trouble with role identification. It is socially awkward to say, ‘this is my brother who just got out of prison’, and ‘I cannot work because I have schizophrenia ’, or ‘I cannot attend because I lost my license for driving drunk’.

In 1997, Dr. Scott's own role identification was threatened. She was told her 20-year course of autoimmune hepatitis caused irreversible cirrhosis, and the only option was liver transplantation. She did not want to take on the role of a patient or a ‘sick’ person, and importantly she did not know how. She scoured the research literature for information that would help her understand what her life would be like during and after transplantation. She found very little. There is extensive evidence about the life saving aspects of transplantation, however, little to assist those individuals who struggle to return to life as they knew it before transplantations. And life after transplantation IS different. Aside from her own situation, as an occupational therapist, she realized if she had this problem, many others likely did also. She has since devoted herself to a research career with the goal of increasing the number of individuals who have access to information and health care services such that they can return to full meaningful participation in life post-transplant. Phase I, revealed that post-transplant participation in a higher number of valued roles as measured by the Role Checklist, is significantly associated with higher SF-36 scores. Phase II is a longitudinal study, measuring timing of return to activities of daily living and valued roles at 15 points over the first 2 years post-transplant. Phase III moved her work into determining the best interventions to support individuals struggling to resume meaningful life participation after transplantation. Her presentations and publications caught the work of colleagues.

Ironically, it was the innovative use, and modification of the Role Checklist, a long standing tool used by occupational therapists, which catapulted her work into the international spotlight. In 2012 she established a formal collaboration with International colleagues and now, in Version 3 of the Role Checklist, with tested translation guidelines and international cross-cultural validation studies in place, her aspiration to establish the first globally accepted measure of participation appears closer than ever.

Dr. Scott's work to enable more individuals to engage in full participation in society, not only following liver transplantation but through establish a cross-culturally valid role participation tool, is another example of how IUPUI's faculty members are translating their research into practice. Dr. Scott is Associate Professor, Occupational Therapy in the IU School of Health and Rehabilitation Sciences.


Congratulations, Professor Scott!

2015 Bantz-Petronio Translating Research into Practice Award

Susan Hickman, PhD, was awarded the 2015 Bantz-Petronio Translating Research into Practice Award in recognition of her exemplary translational research in the area of aging and end of life care.

Dr. Hickman is committed to optimizing the quality of life for older adults in life’s final chapter through improved decision-making and communication about treatment preferences. A primary focus of her research has been on use of the Physician Orders for Life-Sustaining Treatment (POLST) Program to communicate patient treatment preferences as actionable medical orders. This tool helps ensure that patient preferences are known and communicated to improve continuity of care. Findings from her research have been widely disseminated and used to support the development of programs based on the POLST model.

Dr. Hickman also co-founded the Indiana Patient Preferences Coalition, a group of individuals and organizational representatives from across Indiana in law, medicine, nursing, senior care, and ethics. This coalition created Indiana POST (Physician Orders for Scope of Treatment), based on the national POLST model. Dr. Hickman now provides education and facilitation skills training about POST to health care providers around the state. She also serves as the Palliative Care Core lead on a Centers for Medicare and Medicaid Services innovations grant to reduce avoidable hospitalizations and improve the quality of care in 19 Indianapolis-area nursing facilities. Additional work includes a collaboration with colleagues at IU Health that has resulted in the launch of the Encompass Initiative, designed to improve primary palliative care throughout the academic health system.

Dr. Hickman’s work to improve quality of life for older adults in life’s final chapter is another example of how IUPUI’s faculty members are translating their research into practice. Dr. Hickman is Community and Health Systems Professor in the IU School of Nursing and Co-Director, IUPUI Research in Palliative and End-of-Life Communication and Training (RESPECT) Signature Center.


Congratulations, Professor Hickman!

2014 Bantz-Petronio Translating Research into Practice Award

Jeffrey Kline, MD, was awarded the 2014 Bantz-Petronio Translating Research into Practice Award based on his outstanding translational research. Dr. Kline has transformed the way physicians think about, diagnose, and treat pulmonary embolism (PE). The direct application of his work has saved countless lives and prevented unnecessary testing in hundreds of thousands of other patients who present with high risk medical situations. For instance, if you ask an Emergency Medicine physician how they think about PE, you will hear about the PERC rule (Pulmonary Embolism Rule out Criteria). This was created by Dr. Kline and has fundamentally changed the approach to the patient who presents with chest pain or shortness of breath. It is also because the elegance and rigor of his studies, coupled with the clarity of his language, that his work is translated into clinical practice around the world.  

His diagnostic research interests focus on human affect analysis, pretest probability, and novel breath-based instruments to reduce overuse of medical imaging. His human treatment research includes randomized trials of fibrinolysis and inhaled nitric oxide to reduce heart damage from blood clots in the lungs. Dr. Kline’s current work focuses on using the human face as a diagnostic instrument to further help doctors make informed decisions about diagnostic testing for blood clots. His laboratory work focuses on mechanisms and treatment of acute pulmonary hypertension from pulmonary embolism, animal models of pulmonary embolism, and a nanoparticle-delivered enzyme, plasmin, to promote clot lysis without increasing risk. He helped set up an advanced hospital treatment program for patients with severe PE, and he also created and currently runs a clinic specifically to allow patients diagnosed with blood clots in the emergency department to receive treatment at home, rather than in the hospital.

Dr. Kline’s work on an interdisciplinary team including faculty and students focusing on the human face as a diagnostic instrument is an excellent example of the translational research efforts of IUPUI. Dr. Kline is Professor of Emergency Medicine, Professor of Physiology, and Vice Chair of Research in the Department of Emergency Medicine, IU School of Medicine.

Congratulations, Professor Kline!